Born in Argentina, Antonio Spiller had his first violin and viola lessons with his father, Ljerko Spiller, professor of violin and chamber music in Buenos Aires. He made early appearances in chamber music in the United States, South America and Europe, and, supported by the Argentine Mozarteum, made regular appearances as a soloist and chamber musician in South America, after winning several competitions in his native city. After his father, he owes much to Max Rostal, with whom he studied in Cologne for two years on a German government scholarship. In 1978 he was appointed leader of the Bavarian Radio Symphony Orchestra in Munich. He has collaborated with the Joachim Koeckert Quartet, the Munich String Trio and with the pianist Silvia Natiello-Spiller and cellist Wen-Sinn Yang in the Spiller Trio. He was a co-founder of Ingolstadt Orchestra Academy, making it possible for young musicians to play under conductors such as Sir Colin Davis, Kurt Sanderling and Lorin Maazel, as part of a joint foundation with the Academy of the Bavarian Radio Symphony Orchestra.